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Nitric oxide induced S-nitrosation causes base excision repair imbalance

It is well established that inflammation leads to the creation of potent DNA damaging chemicals, including reactive oxygen and nitrogen species. Nitric oxide can react with glutathione to create S-nitrosoglutathione (GSNO), which can in turn lead to S-nitrosated proteins. Of particular interest is t...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Parrish, Marcus C., Chaim, Isaac A., Nagel, Zachary D., Tannenbaum, Steven R., Samson, Leona D., Engelward, Bevin P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436541/
https://ncbi.nlm.nih.gov/pubmed/29929044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.04.008
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