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Wzx flippases exhibiting complex O‐unit preferences require a new model for Wzx–substrate interactions

The Wzx flippase is a critical component of the O‐antigen biosynthesis pathway, being responsible for the translocation of oligosaccharide O units across the inner membrane in Gram‐negative bacteria. Recent studies have shown that Wzx has a strong preference for its cognate O unit, but the types of...

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Détails bibliographiques
Publié dans:Microbiologyopen
Auteurs principaux: Liu, Michael A., Morris, Paraskevi, Reeves, Peter R.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436433/
https://ncbi.nlm.nih.gov/pubmed/29888516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.655
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