Chemical Screening Approaches Enabling Drug Discovery of Autophagy Modulators for Biomedical Applications in Human Diseases

Autophagy is an intracellular degradation pathway for malfunctioning aggregation-prone proteins, damaged organelles, unwanted macromolecules and invading pathogens. This process is essential for maintaining cellular and tissue homeostasis that contribute to organismal survival. Autophagy dysfunction...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Panda, Prashanta Kumar, Fahrner, Alexandra, Vats, Somya, Seranova, Elena, Sharma, Vartika, Chipara, Miruna, Desai, Priyal, Torresi, Jorge, Rosenstock, Tatiana, Kumar, Dhiraj, Sarkar, Sovan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436197/
https://ncbi.nlm.nih.gov/pubmed/30949479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00038
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