The Ciliopathy Gene Ftm/Rpgrip1l Controls Mouse Forebrain Patterning via Region-Specific Modulation of Hedgehog/Gli Signaling

Primary cilia are essential for CNS development. In the mouse, they play a critical role in patterning the spinal cord and telencephalon via the regulation of Hedgehog/Gli signaling. However, despite the frequent disruption of this signaling pathway in human forebrain malformations, the role of prim...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Andreu-Cervera, Abraham, Anselme, Isabelle, Karam, Alice, Laclef, Christine, Catala, Martin, Schneider-Maunoury, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435827/
https://ncbi.nlm.nih.gov/pubmed/30692221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2199-18.2019
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