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Hyperexcitability and Hyperplasticity Disrupt Cerebellar Signal Transfer in the IB2 KO Mouse Model of Autism

Autism spectrum disorders (ASDs) are pervasive neurodevelopmental conditions that often involve mutations affecting synaptic mechanisms. Recently, the involvement of cerebellum in ASDs has been suggested, but the underlying functional alterations remained obscure. We investigated single-neuron and m...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Soda, Teresa, Mapelli, Lisa, Locatelli, Francesca, Botta, Laura, Goldfarb, Mitchell, Prestori, Francesca, D'Angelo, Egidio
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435825/
https://ncbi.nlm.nih.gov/pubmed/30696733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1985-18.2019
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