Hyperexcitability and Hyperplasticity Disrupt Cerebellar Signal Transfer in the IB2 KO Mouse Model of Autism

Autism spectrum disorders (ASDs) are pervasive neurodevelopmental conditions that often involve mutations affecting synaptic mechanisms. Recently, the involvement of cerebellum in ASDs has been suggested, but the underlying functional alterations remained obscure. We investigated single-neuron and m...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Soda, Teresa, Mapelli, Lisa, Locatelli, Francesca, Botta, Laura, Goldfarb, Mitchell, Prestori, Francesca, D'Angelo, Egidio
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2019
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435825/
https://ncbi.nlm.nih.gov/pubmed/30696733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1985-18.2019
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