Hyperexcitability and Hyperplasticity Disrupt Cerebellar Signal Transfer in the IB2 KO Mouse Model of Autism

Autism spectrum disorders (ASDs) are pervasive neurodevelopmental conditions that often involve mutations affecting synaptic mechanisms. Recently, the involvement of cerebellum in ASDs has been suggested, but the underlying functional alterations remained obscure. We investigated single-neuron and m...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Soda, Teresa, Mapelli, Lisa, Locatelli, Francesca, Botta, Laura, Goldfarb, Mitchell, Prestori, Francesca, D'Angelo, Egidio
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2019
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435825/
https://ncbi.nlm.nih.gov/pubmed/30696733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1985-18.2019
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