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Mitochondria transfer from mesenchymal stem cells structurally and functionally repairs renal proximal tubular epithelial cells in diabetic nephropathy in vivo

The underlying therapeutic mechanism of renal tubular epithelium repair of diabetic nephropathy (DN) by bone marrow-derived mesenchymal stem cells (BM-MSCs) has not been fully elucidated. Recently, mitochondria (Mt) transfer was reported as a novel action of BM-MSCs to rescue injured cells. We inves...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Konari, Naoto, Nagaishi, Kanna, Kikuchi, Shin, Fujimiya, Mineko
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435708/
https://ncbi.nlm.nih.gov/pubmed/30914727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40163-y
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