An integrated whole genome analysis of Mycobacterium tuberculosis reveals insights into relationship between its genome, transcriptome and methylome

Human tuberculosis disease (TB), caused by Mycobacterium tuberculosis (Mtb), is a complex disease, with a spectrum of outcomes. Genomic, transcriptomic and methylation studies have revealed differences between Mtb lineages, likely to impact on transmission, virulence and drug resistance. However, so...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gomez-Gonzalez, Paula J., Andreu, Nuria, Phelan, Jody E., de Sessions, Paola Florez, Glynn, Judith R., Crampin, Amelia C., Campino, Susana, Butcher, Philip D., Hibberd, Martin L., Clark, Taane G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435705/
https://ncbi.nlm.nih.gov/pubmed/30914757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41692-2
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