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Highly Mutable Linker Regions Regulate HIV-1 Rev Function and Stability
HIV-1 Rev is an essential viral regulatory protein that facilitates the nuclear export of intron-containing viral mRNAs. It is organized into structured, functionally well-characterized motifs joined by less understood linker regions. Our recent competitive deep mutational scanning study confirmed m...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6435700/ https://ncbi.nlm.nih.gov/pubmed/30914719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41582-7 |
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