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Synergy between the alteration in the N-terminal region of butyrylcholinesterase K variant and apolipoprotein E4 in late-onset Alzheimer’s disease

While the life expectancy of the population has increased, Alzheimer’s disease (AD) has emerged as one of the greatest health problems of old age. AD is characterized by neuronal loss and cognitive decline. In the AD brain, there is a decrease in levels of acetylcholinesterase (AChE) and an increase...

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發表在:Sci Rep
Main Authors: Jasiecki, Jacek, Limon-Sztencel, Anna, Żuk, Monika, Chmara, Magdalena, Cysewski, Dominik, Limon, Janusz, Wasąg, Bartosz
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435664/
https://ncbi.nlm.nih.gov/pubmed/30914707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41578-3
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