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Low survival rate and muscle fiber-dependent aging effects in the McArdle disease mouse model
McArdle disease is an autosomal recessive disorder caused by the absence of the muscle glycogen phosphorylase, which leads to impairment of glycogen breakdown. The McArdle mouse, a model heavily affected by glycogen accumulation and exercise intolerance, was used to characterize disease progression...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6435661/ https://ncbi.nlm.nih.gov/pubmed/30914683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41414-8 |
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