Activin A regulates the epidermal growth factor receptor promoter by activating the PI3K/SP1 pathway in oral squamous cell carcinoma cells

Epidermal growth factor receptor (EGFR) and activin A are both overexpressed in oral cavity squamous cell carcinoma (OSCC). We evaluated their clinical correlation and activin A-mediated EGFR regulation in this study. Overexpression of both transcripts/proteins indicated a poorer prognosis in OSCC p...

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Publicat a:Sci Rep
Autors principals: Tsai, Chi-Neu, Tsai, Chia-Lung, Yi, Jui-Shan, Kao, Huang-Kai, Huang, Yenlin, Wang, Chun-I, Lee, Yun-Shien, Chang, Kai-Ping
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435638/
https://ncbi.nlm.nih.gov/pubmed/30914776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41396-7
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