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Down-regulation of HIF-1α inhibits the proliferation, migration, and invasion of gastric cancer by inhibiting PI3K/AKT pathway and VEGF expression

In view of the high incidence of gastric cancer and the functions of hypoxia-inducible factor 1α (HIF-1α), our study aimed to investigate the functionality of HIF-1α in gastric cancer, and to explore the diagnostic and prognostic values of HIF-1α for this disease. Expression of HIF-1α in tumor tissu...

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Podrobná bibliografie
Vydáno v:Biosci Rep
Hlavní autoři: Zhang, Jingjing, Xu, Jun, Dong, Yonghong, Huang, Bo
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435555/
https://ncbi.nlm.nih.gov/pubmed/29899167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20180741
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