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PPARγ regulates meibocyte differentiation and lipid synthesis of cultured human meibomian gland epithelial cells (hMGEC)

PURPOSE: To evaluate the role of PPARγ in regulating meibocyte differentiation and lipid synthesis in a human meibomian gland epithelial cell line (hMGEC). METHODS: HMGEC were exposed to the PPARγ agonist, Rosiglitazone, from 10–50 μM. Cultures were also exposed to specific PPARγ antagonist, T007090...

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Detalhes bibliográficos
Publicado no:Ocul Surf
Main Authors: Kim, Sun Woong, Xie, Yilu, Nguyen, Paul Q., Bui, Vickie T., Huynh, Kelly, Kang, Jonathan S., Brown, Donald J., Jester, James V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434942/
https://ncbi.nlm.nih.gov/pubmed/29990545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtos.2018.07.004
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