Discordant association of the CREBRF rs373863828 A-allele with increased body mass index and protection from type 2 diabetes in Māori and Pacific (Polynesian) people living in Aotearoa New Zealand

AIM/HYPOTHESES: The A (minor) allele of CREBRF rs373863828 associates with increased body mass index (BMI) and reduced risk of type 2 diabetes (T2D) in the Samoan population of Samoa and American Samoa. Our aim was to test rs373863828 for association with BMI and odds of T2D, gout and chronic kidney...

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Pubblicato in:Diabetologia
Autori principali: Krishnan, Mohanraj, Major, Tanya J, Topless, Ruth K, Dewes, Ofa, Yu, Lennex, Thompson, John MD, McCowan, Lesley, de Zoysa, Janak, Stamp, Lisa K, Dalbeth, Nicola, Hindmarsh, Jennie Harré, Rapana, Nuku, Deka, Ranjan, Eng, Winston W H, Weeks, Daniel E, Minster, Ryan L, McGarvey, Stephen T, Viali, Satupa’itea, Naseri, Take, Reupena, Muagututi’a Sefuiva, Wilcox, Phillip, Grattan, David, Shepherd, Peter R, Shelling, Andrew N, Murphy, Rinki, Merriman, Tony R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434933/
https://ncbi.nlm.nih.gov/pubmed/29721634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-018-4623-1
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