Deciphering the mechanism of Indirubin and its derivatives in the inhibition of Imatinib resistance using a “drug target prediction-gene microarray analysis-protein network construction” strategy

BACKGROUND: The introduction of imatinib revolutionized the treatment of chronic myeloid leukaemia (CML), substantially extending patient survival. However, imatinib resistance is currently a clinical problem for CML. It is very importantto find a strategy to inhibit imatinib resistance. METHODS: (1...

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Vydáno v:BMC Complement Altern Med
Hlavní autoři: Li, Huayao, Liu, Lijuan, Zhuang, Jing, Liu, Cun, Zhou, Chao, Yang, Jing, Gao, Chundi, Liu, Gongxi, Sun, Changgang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434895/
https://ncbi.nlm.nih.gov/pubmed/30909944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-019-2471-2
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