Store depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer’s disease

Voltage-gated ion channels are critical for neuronal integration. Some of these channels, however, are mis-regulated in several neurological disorders, causing both gain- and loss-of-function channelopathies in neurons. Using several transgenic mouse models of Alzheimer’s disease (AD), we find that...

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Detalhes bibliográficos
Publicado no:Neurobiol Learn Mem
Main Authors: Musial, Timothy F., Molina-Campos, Elizabeth, Bean, Linda A., Ybarra, Natividad, Borenstein, Ronen, Russo, Matthew L., Buss, Eric W., Justus, Daniel, Neuman, Krystina M., Ayala, Gelique D., Mullen, Sheila A., Voskobiynyk, Yuliya, Tulisiak, Christopher T., Fels, Jasmine A., Corbett, Nicola J., Carballo, Gabriel, Kennedy, Colette D., Popovic, Jelena, Ramos-Franco, Josefina, Fill, Michael, Pergande, Melissa R., Borgia, Jeffrey A., Corbett, Grant T., Pahan, Kalipada, Han, Ye, Chetkovich, Dane M., Vassar, Robert J., Byrne, Richard W., Oh, M. Matthew, Stoub, Travis R., Remy, Stefan, Disterhoft, John F., Nicholson, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434702/
https://ncbi.nlm.nih.gov/pubmed/29906573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nlm.2018.06.004
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