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Direct reprogramming of fibroblasts into Smooth Muscle-Like Cells with Defined Transcription Factors

OBJECTIVE: To identify transcription factors that could contribute to direct reprogramming of fibroblasts towards smooth muscle cell fate. APPROACH AND RESULTS: We screened various combinations of transcription factors, including Myocd, Mef2C, Mef2B, Mkl1, Gata4, Gata5, Gata6, Ets1, and their corres...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Hirai, Hiroyuki, Yang, Bo, Garcia-Barrio, Minerva T., Rom, Oren, Ma, Peter X., Zhang, Jifeng, Chen, Y. Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434534/
https://ncbi.nlm.nih.gov/pubmed/30026272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.310870
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