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Platelet dysfunction during trauma involves diverse signaling pathways and an inhibitory activity in patient-derived plasma

BACKGROUND: Trauma-induced coagulopathy (TIC) occurs in about 25% of injured patients and accounts for about 10% of deaths worldwide. Upon injury, hemostatic function may decline due to vascular dysfunction, clotting factor deficiencies, hyperfibrinolysis, and/or platelet dysfunction. We investigate...

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Detalhes bibliográficos
Publicado no:J Trauma Acute Care Surg
Main Authors: Verni, Christopher C., Davila, Antonio, Balian, Steve, Sims, Carrie A., Diamond, Scott L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434531/
https://ncbi.nlm.nih.gov/pubmed/30531331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000002140
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