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Reduced Amount or Integrity of Arterial Elastic Fibers Alters Allometric Scaling Relationships for Aortic Diameter and Heart Weight, But Not Cardiac Function in Maturing Mice
Allometric scaling laws relate physiologic parameters to body weight. Genetically modified mice allow investigation of allometric scaling laws when fundamental cardiovascular components are altered. Elastin haploinsufficient (Eln(+/−)) mice have reduced elastin amounts, and fibulin-5 knockout (Fbln5...
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| Publicado no: | J Biomech Eng |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Mechanical Engineers
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6434326/ https://ncbi.nlm.nih.gov/pubmed/30729980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1115/1.4042766 |
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