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Changes of Bax, Bcl-2, CCR-2, MCP-1, and TGF-β1 genes in the left ventricle of spontaneously hypertensive rat after losartan treatment

PURPOSE: Increased apoptosis was recently found in the hypertrophied left ventricle of spontaneously hypertensive rats (SHRs). Although the available evidence suggests that apoptosis can be induced in cardiac cells by various insults including pressure overload, cardiac apoptosis appears to result f...

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Publicat a:Korean J Pediatr
Autors principals: Lee, Hyeryon, Kim, Kwan Chang, Hong, Young Mi
Format: Artigo
Idioma:Inglês
Publicat: Korean Pediatric Society 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434229/
https://ncbi.nlm.nih.gov/pubmed/30360036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3345/kjp.2018.06856
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