CAEV Vif Hijacks ElonginB/C, CYPA and Cullin5 to Assemble the E3 Ubiquitin Ligase Complex Stepwise to Degrade oaA3Z2-Z3

Caprine arthritis encephalitis virus (CAEV) is a lentivirus that causes multisystemic chronic disorders in sheep and goats. It encodes Vif to counteract the restriction of Ovis aries A3Z2-Z3 (oaA3Z2-Z3) by inducing their degradation. Nevertheless, the mechanisms underlying the interplay between CAEV...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Zhao, Zhilei, Li, Zhaolong, Huan, Chen, Wang, Hong, Su, Xing, Zhang, Wenyan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6434172/
https://ncbi.nlm.nih.gov/pubmed/30941116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.00565
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