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Position 123 of halohydrin dehalogenase HheG plays an important role in stability, activity, and enantioselectivity
HheG from Ilumatobacter coccineus is a halohydrin dehalogenase with synthetically useful activity in the ring opening of cyclic epoxides with various small anionic nucleophiles. This enzyme provides access to chiral β-substituted alcohols that serve as building blocks in the pharmaceutical industry....
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| Publicado no: | Sci Rep |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6434027/ https://ncbi.nlm.nih.gov/pubmed/30911023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41498-2 |
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