The Emerging Role of Complement Proteins as a Target for Therapy of IgA Nephropathy

IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide and a common cause of end-stage renal disease. Evaluation of a kidney biopsy is necessary for diagnosis, with routine immunofluorescence microscopy revealing dominant or co-dominant IgA immunodeposits usually with...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Rizk, Dana V., Maillard, Nicolas, Julian, Bruce A., Knoppova, Barbora, Green, Todd J., Novak, Jan, Wyatt, Robert J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433978/
https://ncbi.nlm.nih.gov/pubmed/30941137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00504
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