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Therapeutic Targeting of Cancer Stem Cells: Integrating and Exploiting the Acidic Niche

Cancer stem cells (CSC) or tumor-initiating cells represent a small subpopulation of cells within the tumor bulk that share features with somatic stem cells, such as self-renewal and pluripotency. From a clinical point of view, CSC are thought to be the main drivers of tumor relapse in patients by s...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Vander Linden, Catherine, Corbet, Cyril
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433943/
https://ncbi.nlm.nih.gov/pubmed/30941310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00159
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