Differential Targeting of c-Maf, Bach-1, and Elmo-1 by microRNA-143 and microRNA-365 Promotes the Intracellular Growth of Mycobacterium tuberculosis in Alternatively IL-4/IL-13 Activated Macrophages

Mycobacterium tuberculosis (Mtb) can subvert the host defense by skewing macrophage activation toward a less microbicidal alternative activated state to avoid classical effector killing functions. Investigating the molecular basis of this evasion mechanism could uncover potential candidates for host...

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Udgivet i:Front Immunol
Main Authors: Tamgue, Ousman, Gcanga, Lorna, Ozturk, Mumin, Whitehead, Lauren, Pillay, Shandre, Jacobs, Raygaana, Roy, Sugata, Schmeier, Sebastian, Davids, Malika, Medvedeva, Yulia A., Dheda, Keertan, Suzuki, Harukazu, Brombacher, Frank, Guler, Reto
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433885/
https://ncbi.nlm.nih.gov/pubmed/30941122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00421
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