Impact of Age on the Efficacy and Safety of Alirocumab in Patients with Heterozygous Familial Hypercholesterolemia

PURPOSE: This post-hoc analysis examined whether age modified the efficacy and safety of alirocumab, a PCSK9 inhibitor, in patients with heterozygous familial hypercholesterolemia (HeFH), using pooled data from four 78-week placebo-controlled phase 3 trials (ODYSSEY FH I, FH II, LONG TERM, and HIGH...

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Bibliographic Details
Published in:Cardiovasc Drugs Ther
Main Authors: Ginsberg, Henry N., Tuomilehto, Jaakko, Hovingh, G. Kees, Cariou, Bertrand, Santos, Raul D., Brown, Alan S., Sanganalmath, Santosh K., Koren, Andrew, Thompson, Desmond, Raal, Frederick J.
Format: Artigo
Language:Inglês
Published: Springer US 2019
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Short Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433806/
https://ncbi.nlm.nih.gov/pubmed/30734207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-019-06852-6
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