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Acetyltransferase p300 inhibitor reverses hypertension‐induced cardiac fibrosis

Epigenetic dysregulation plays a crucial role in cardiovascular diseases. Previously, we reported that acetyltransferase p300 (ATp300) inhibitor L002 prevents hypertension‐induced cardiac hypertrophy and fibrosis in a murine model. In this short communication, we show that treatment of hypertensive...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Rai, Rahul, Sun, Tianjiao, Ramirez, Veronica, Lux, Elizabeth, Eren, Mesut, Vaughan, Douglas E., Ghosh, Asish K.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433695/
https://ncbi.nlm.nih.gov/pubmed/30710427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14162
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