Inhibition of PAI‐1 limits chemotherapy resistance in lung cancer through suppressing myofibroblast characteristics of cancer‐associated fibroblasts

Plasminogen activator inhibitor‐1 (PAI‐1) promotes pulmonary fibrosis through increasing myofibroblast (MF) characteristics, expressing alpha‐smooth muscle actin (α‐SMA) in fibroblasts. Fibroblasts in the tumour stroma are called cancer‐associated fibroblasts (CAFs). Some CAFs have MF characteristic...

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Detaylı Bibliyografya
Yayımlandı:J Cell Mol Med
Asıl Yazarlar: Masuda, Takeshi, Nakashima, Taku, Namba, Masashi, Yamaguchi, Kakuhiro, Sakamoto, Shinjiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Miyata, Yoshihiro, Hamada, Hironobu, Okada, Morihito, Hattori, Noboru
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433668/
https://ncbi.nlm.nih.gov/pubmed/30734495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14205
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