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Betulinic acid alleviates endoplasmic reticulum stress‐mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice

BACKGROUND AND PURPOSE: The molecular mechanism for the pathogenesis of nonalcoholic fatty liver disease (NAFLD) remains elusive. Both farnesoid X receptor (FXR) signalling and endoplasmic reticulum (ER) stress contribute to the progression of NAFLD; however, it is not clear whether the actions of t...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Gu, Ming, Zhao, Ping, Zhang, Shiying, Fan, Shengjie, Yang, Li, Tong, Qingchun, Ji, Guang, Huang, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433649/
https://ncbi.nlm.nih.gov/pubmed/30635917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14570
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