ParB dynamics and the critical role of the CTD in DNA condensation unveiled by combined force-fluorescence measurements

Bacillus subtilis ParB forms multimeric networks involving non-specific DNA binding leading to DNA condensation. Previously, we found that an excess of the free C-terminal domain (CTD) of ParB impeded DNA condensation or promoted decondensation of pre-assembled networks (Fisher et al., 2017). Howeve...

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Pubblicato in:eLife
Autori principali: Madariaga-Marcos, Julene, Pastrana, Cesar L, Fisher, Gemma LM, Dillingham, Mark Simon, Moreno-Herrero, Fernando
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2019
Soggetti:
Chromosomes and Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433461/
https://ncbi.nlm.nih.gov/pubmed/30907359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43812
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