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Spontaneously slow-cycling subpopulations of human cells originate from activation of stress-response pathways

Slow-cycling subpopulations exist in bacteria, yeast, and mammalian systems. In the case of cancer, slow-cycling subpopulations have been proposed to give rise to drug resistance. However, the origin of slow-cycling human cells is poorly studied, in large part due to lack of markers to identify thes...

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Vydáno v:PLoS Biol
Hlavní autoři: Min, Mingwei, Spencer, Sabrina L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433297/
https://ncbi.nlm.nih.gov/pubmed/30865623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000178
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