LINE-2 transposable elements are a source of functional human microRNAs and target sites

Transposable elements (TEs) are dynamically expressed at high levels in multiple human tissues, but the function of TE-derived transcripts remains largely unknown. In this study, we identify numerous TE-derived microRNAs (miRNAs) by conducting Argonaute2 RNA immunoprecipitation followed by small RNA...

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Udgivet i:PLoS Genet
Main Authors: Petri, Rebecca, Brattås, Per Ludvik, Sharma, Yogita, Jönsson, Marie E., Pircs, Karolina, Bengzon, Johan, Jakobsson, Johan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433296/
https://ncbi.nlm.nih.gov/pubmed/30865625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008036
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