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Synergy among non-desmoglein antibodies contributes to the immunopathology of desmoglein antibody–negative pemphigus vulgaris

Pemphigus vulgaris (PV) is a potentially lethal mucocutaneous blistering disease characterized by IgG autoantibodies (AuAbs) binding to epidermal keratinocytes and inducing this devastating disease. Here, we observed that non-desmoglein (Dsg) AuAbs in the sera of patients with Dsg1/3 AuAb–negative a...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Chernyavsky, Alex, Amber, Kyle T., Agnoletti, Arianna F., Wang, Candice, Grando, Sergei A.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433052/
https://ncbi.nlm.nih.gov/pubmed/30692201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006743
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