Lateral distribution of phosphatidylinositol 4,5-bisphosphate in membranes regulates formin- and ARP2/3-mediated actin nucleation

Spatial and temporal control of actin polymerization is fundamental for many cellular processes, including cell migration, division, vesicle trafficking, and response to agonists. Many actin-regulatory proteins interact with phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) and are either activate...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Bucki, Robert, Wang, Yu-Hsiu, Yang, Changsong, Kandy, Sreeja Kutti, Fatunmbi, Ololade, Bradley, Ryan, Pogoda, Katarzyna, Svitkina, Tatyana, Radhakrishnan, Ravi, Janmey, Paul A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Membrane Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433049/
https://ncbi.nlm.nih.gov/pubmed/30692198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005552
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