Schistosoma mansoni Coinfection Attenuates Murine Toxoplasma gondii-Induced Crohn's-Like Ileitis by Preserving the Epithelial Barrier and Downregulating the Inflammatory Response

Background and aims: Mice orally infected with T. gondii develop Crohn's disease (CD)-like enteritis associated with severe mucosal damage and a systemic inflammatory response, resulting in high morbidity and mortality. Previously, helminthic infections have shown therapeutic potential in exper...

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izdano v:Front Immunol
Main Authors: Pêgo, Beatriz, Martinusso, Cesonia A., Bernardazzi, Claudio, Ribeiro, Beatriz Elias, de Araujo Cunha, Aline Fernandes, de Souza Mesquita, Jacilene, Nanini, Hayandra F., Machado, Marcelo Pelajo, Castelo-Branco, Morgana T. L., Cavalcanti, Marta Guimarães, de Souza, Heitor S. P.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432985/
https://ncbi.nlm.nih.gov/pubmed/30936867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00442
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