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PPAR-gamma pathways attenuate pulmonary granuloma formation in a carbon nanotube induced murine model of sarcoidosis

Peroxisome proliferator activated receptor gamma (PPARγ), a ligand activated nuclear transcription factor, is constitutively expressed in alveolar macrophages of healthy individuals. PPARγ deficiencies have been noted in several lung diseases including the alveolar macrophages of pulmonary sarcoidos...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: McPeek, Matthew, Malur, Anagha, Tokarz, Debra A., Murray, Gina, Barna, Barbara P., Thomassen, Mary Jane
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432932/
https://ncbi.nlm.nih.gov/pubmed/29908181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.06.061
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