Expression of AR-V7 and ARv(567es) in circulating tumor cells correlates with outcomes to taxane therapy in men with metastatic prostate cancer treated in TAXYNERGY

PURPOSE: Biomarkers aiding treatment optimization in metastatic castration-resistant prostate cancer (mCRPC) are scarce. Presence or absence of androgen receptor (AR) splice variants, AR-V7 and AR(v567es), in mCRPC patient circulating tumor cells (CTCs) may be associated with taxane treatment outcom...

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Udgivet i:Clin Cancer Res
Main Authors: Tagawa, Scott T., Antonarakis, Emmanuel S., Gjyrezi, Ada, Galletti, Giuseppe, Kim, Seaho, Worroll, Daniel, Stewart, John, Zaher, Atef, Szatrowski, Ted P., Ballman, Karla V., Kita, Katsuhiro, Tasaki, Shinsuke, Bai, Yang, Portella, Luigi, Kirby, Brian J, Saad, Fred, Eisenberger, Mario A., Nanus, David M., Giannakakou, Paraskevi
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432911/
https://ncbi.nlm.nih.gov/pubmed/30301829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0320
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