Development of Poly(ɛ-Caprolactone) Scaffold Loaded with Simvastatin and Beta-Cyclodextrin Modified Hydroxyapatite Inclusion Complex for Bone Tissue Engineering

In this study, we developed poly(ɛ-caprolactone) (PCL) 3D scaffolds using a solid free form fabrication (SFF) technique. β-cyclodextrin (βCD) was grafted to hydroxyapatite (HAp) and this βCD grafted HAp was coated onto the PCL scaffold surface, followed by drug loading through an inclusion complex i...

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Detalhes bibliográficos
Publicado no:Polymers (Basel)
Main Authors: Lee, Jung Bok, Kim, Ji Eun, Bae, Min Soo, Park, Su A, Balikov, Daniel A., Sung, Hak-joon, Jeon, Hoon Bong, Park, Hun Kuk, Um, Soong Ho, Lee, Kook Sun, Kwon, Il Keun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432564/
https://ncbi.nlm.nih.gov/pubmed/30979140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym8020049
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