pH-Triggered Sheddable Shielding System for Polycationic Gene Carriers

For improving the therapeutic efficiency of tumors and decreasing undesirable side effects, ternary complexes were developed by coating pH-sensitive PEG-b-PLL-g-succinylsulfathiazole (hereafter abbreviated as PPSD) with DNA/PEI polyplexes via electrostatic interaction. PPSD can efficiently shield th...

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Bibliographic Details
Published in:Polymers (Basel)
Main Authors: Xia, Jialiang, Tian, Huayu, Chen, Jie, Lin, Lin, Guo, Zhaopei, Han, Bing, Yang, Hongyan, Feng, Zongcai
Format: Artigo
Language:Inglês
Published: MDPI 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432142/
https://ncbi.nlm.nih.gov/pubmed/30979234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym8040141
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