High Expression of LTBP2 Contributes to Poor Prognosis in Colorectal Cancer Patients and Correlates with the Mesenchymal Colorectal Cancer Subtype

Colorectal cancer (CRC) is a complex and heterogeneous disease with four consensus molecular subtypes (CMS1-4). LTBP2 is a member of the fibrillin/LTBP super family and plays a critical role in tumorigenesis by activating TGF-β in the CMS4 CRC subtype. So far, the expression and prognostic significa...

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Опубликовано в: :Dis Markers
Главные авторы: Huang, Ying, Wang, Guihua, Zhao, Chunmei, Geng, Rong, Zhang, Shu, Wang, Wei, Chen, Jing, Liu, Huimin, Wang, Xudong
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2019
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431450/
https://ncbi.nlm.nih.gov/pubmed/30956730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5231269
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