Infection by the parasitic helminth Trichinella spiralis activates a Tas2r-mediated signaling pathway in intestinal tuft cells

The parasitic helminth Trichinella spiralis, which poses a serious health risk to animals and humans, can be found worldwide. Recent findings indicate that a rare type of gut epithelial cell, tuft cells, can detect the helminth, triggering type 2 immune responses. However, the underlying molecular m...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Luo, Xiao-Cui, Chen, Zhen-Huang, Xue, Jian-Bo, Zhao, Dong-Xiao, Lu, Chen, Li, Yi-Hong, Li, Song-Min, Du, Ya-Wen, Liu, Qun, Wang, Ping, Liu, Mingyuan, Huang, Liquan
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431192/
https://ncbi.nlm.nih.gov/pubmed/30819885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812901116
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