A strategy for generating cancer-specific monoclonal antibodies to aberrant O-glycoproteins: identification of a novel dysadherin-Tn antibody

Successful application of potent antibody-based T-cell engaging immunotherapeutic strategies is currently limited mainly to hematological cancers. One major reason is the lack of well-characterized antigens on solid tumors with sufficient cancer specific expression. Aberrantly O-glycosylated protein...

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Detalhes bibliográficos
Publicado no:Glycobiology
Main Authors: Steentoft, Catharina, Fuhrmann, Max, Battisti, Federico, Van Coillie, Julie, Madsen, Thomas D, Campos, Diana, Halim, Adnan, Vakhrushev, Sergey Y, Joshi, Hiren J, Schreiber, Hans, Mandel, Ulla, Narimatsu, Yoshiki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Regular Manuscripts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430981/
https://ncbi.nlm.nih.gov/pubmed/30726901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwz004
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