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FGF-23 Deficiency Impairs Hippocampal-Dependent Cognitive Function

Fibroblast growth factor receptor (FGFR) and α-Klotho transduce FGF-23 signaling in renal tubules to maintain systemic phosphate/vitamin D homeostasis. Mice deficient for either the ligand, FGF-23, or the co-receptor, Klotho, are phenocopies with both showing rapid and premature development of multi...

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Publicado en:eNeuro
Main Authors: Laszczyk, Ann M., Nettles, Dailey, Pollock, Tate A., Fox, Stephanie, Garcia, Melissa L., Wang, Jing, Quarles, L. Darryl, King, Gwendalyn D.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430630/
https://ncbi.nlm.nih.gov/pubmed/30911673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0469-18.2019
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