An Easy and Sensitive Method to Profile the Antibody Specificities of HLA–specific Memory B Cells

BACKGROUND. Pretransplant immunological risk assessment is currently based on donor–specific HLA antibodies in serum. Despite being an excellent source for antibodies produced by bone marrow–residing plasma cells, serum analysis does not provide information on the memory B–cell compartment. Although...

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Vydáno v:Transplantation
Hlavní autoři: Karahan, Gonca E., Krop, Juliette, Wehmeier, Caroline, de Vaal, Yvonne J.H., Langerak–Langerak, Janneke, Roelen, Dave L., Lardy, Neubury M., Bemelman, Frederike J., ten Berge, Ineke J.M., Reinders, Marlies E.J., van Kooten, Cees, Claas, Frans H.J., Heidt, Sebastiaan
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2019
Témata:
Original Basic Science—General
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430593/
https://ncbi.nlm.nih.gov/pubmed/30418423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000002516
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