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GADD45γ Activated Early in the Course of Herpes Simplex Virus 1 Infection Suppresses the Activation of a Network of Innate Immunity Genes

The stress response genes encoding GADD45γ, and to a lesser extent GADD45β, are activated early in infection with herpes simplex virus 1 (HSV-1). Cells that had been depleted of GADD45γ by transfection of short hairpin RNA (shRNA) or in which the gene had been knocked out (ΔGADD45γ) yielded signific...

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Vydáno v:J Virol
Hlavní autoři: She, Mingmin, Jiang, Haifang, Chen, Xiaoxiang, Chen, Xiaoqing, Liu, Xianjie, Zhang, Xueyan, Roizman, Bernard, Zhou, Grace G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430557/
https://ncbi.nlm.nih.gov/pubmed/30700604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02201-18
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