Validating Enterovirus D68-2A(pro) as an Antiviral Drug Target and the Discovery of Telaprevir as a Potent D68-2A(pro) Inhibitor

Enterovirus D68 (EV-D68) is a viral pathogen that leads to severe respiratory illness and has been linked with the development of acute flaccid myelitis (AFM) in children. No vaccines or antivirals are currently available for EV-D68 infection, and treatment options for hospitalized patients are limi...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Musharrafieh, Rami, Ma, Chunlong, Zhang, Jiantao, Hu, Yanmei, Diesing, Jessica M., Marty, Michael T., Wang, Jun
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430540/
https://ncbi.nlm.nih.gov/pubmed/30674624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02221-18
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