Baseline identification of clonal V(D)J sequences for DNA-based minimal residual disease detection in multiple myeloma

Tracking of clonal immunoglobulin V(D)J rearrangement sequences by next generation sequencing is highly sensitive for minimal residual disease in multiple myeloma. However, previous studies have found variable rates of V(D)J sequence identification at baseline, which could limit tracking. Here, we a...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Rustad, Even H., Hultcrantz, Malin, Yellapantula, Venkata D., Akhlaghi, Theresia, Ho, Caleb, Arcila, Maria E., Roshal, Mikhail, Patel, Akshar, Chen, Denise, Devlin, Sean M., Jacobsen, Austin, Huang, Ying, Miller, Jeffrey E., Papaemmanuil, Elli, Landgren, Ola
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430394/
https://ncbi.nlm.nih.gov/pubmed/30901326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211600
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