Baseline identification of clonal V(D)J sequences for DNA-based minimal residual disease detection in multiple myeloma

Tracking of clonal immunoglobulin V(D)J rearrangement sequences by next generation sequencing is highly sensitive for minimal residual disease in multiple myeloma. However, previous studies have found variable rates of V(D)J sequence identification at baseline, which could limit tracking. Here, we a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rustad, Even H., Hultcrantz, Malin, Yellapantula, Venkata D., Akhlaghi, Theresia, Ho, Caleb, Arcila, Maria E., Roshal, Mikhail, Patel, Akshar, Chen, Denise, Devlin, Sean M., Jacobsen, Austin, Huang, Ying, Miller, Jeffrey E., Papaemmanuil, Elli, Landgren, Ola
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430394/
https://ncbi.nlm.nih.gov/pubmed/30901326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211600
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