Hepatocytes direct the formation of a pro-metastatic niche in the liver.

The liver is the most common site of metastatic disease(1). While this metastatic tropism may reflect mechanical trapping of circulating tumor cells, liver metastasis is also dependent, at least in part, on formation of a “pro-metastatic” niche that supports tumor cell spread to the liver(2,3). Mech...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Lee, Jae W., Stone, Meredith L., Porrett, Paige M., Thomas, Stacy K., Komar, Chad A., Li, Joey H., Delman, Devora, Graham, Kathleen, Gladney, Whitney L., Hua, Xia, Black, Taylor A., Chien, Austin L., Majmundar, Krishna S., Thompson, Jeffrey C., Yee, Stephanie S., O’Hara, Mark H., Aggarwal, Charu, Xin, Dong, Shaked, Abraham, Gao, Mingming, Liu, Dexi, Borad, Mitesh J., Ramanathan, Ramesh K., Carpenter, Erica L., Ji, Ailing, de Beer, Maria C., de Beer, Frederick C., Webb, Nancy R., Beatty, Gregory L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430113/
https://ncbi.nlm.nih.gov/pubmed/30842658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1004-y
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