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Non-acylated Wnts can promote signaling

Wnts are a family of 19 extracellular ligands that regulate cell fate, proliferation and migration during metazoan embryogenesis and throughout adulthood. Wnts are acylated post-translationally at a conserved serine and bind the extracellular cysteine-rich domain (CRD) of Frizzled (FZD) seven-pass t...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Speer, Kelsey F., Sommer, Anselm, Tajer, Benjamin, Mullins, Mary C., Klein, Peter S., Lemmon, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429962/
https://ncbi.nlm.nih.gov/pubmed/30673610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.12.104
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