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Relationship between serum osteocalcin/undercarboxylated osteocalcin and type 2 diabetes: a systematic review/meta-analysis study protocol

INTRODUCTION: The global burden of type 2 diabetes (T2DM) is steadily increasing. Experimental studies have demonstrated that a novel hormone secreted by bone cells, osteocalcin (OC), can stimulate beta-cell proliferation and improve insulin sensitivity in mice. Observational studies in humans have...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Liu, Yihui, Liu, Xiaoying, R Lewis, Joshua, Brock, Kaye, C Brennan-Speranza, Tara, Teixeira-Pinto, Armando
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429918/
https://ncbi.nlm.nih.gov/pubmed/30862632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2018-023918
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